@nagaya_masashi @uIPau9hTV21Dn8c @mihiro3636A そか、

2025年10月12日

@nagaya_masashi @uIPau9hTV21Dn8c @mihiro3636A そか、

— 銃とバッジを置いていけ＆ニチカン　共同運営アカウントをスタート (@kokosatoh)
Oct 11, 2025

from Twitter https://twitter.com/kokosatoh

October 12, 2025 at 03:59AM
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一般ニュース解説

@coinspace_ 今回はマジやばいな

@freedomrugya なわけない

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2025年10月26日 9:44 PM
can steroids cause kidney failure
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2025年10月30日 10:22 AM
truth about anabolic steroids
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Réponses aux questions courantes sur le clenbutérolより:
2025年11月1日 8:59 AM
At physiologic testosterone ranges, almost all androgen receptors are engaged.
Therefore, supraphysiologic doses of testosterone or AASs would haven’t any elevated anabolic effect in wholesome athletes unless other mechanisms of motion existed.
Some information about the improvement of clitoromegaly can be found
from analysis in female-to-male transsexual sufferers.
In one research, stretched clitoral size elevated from 1.4 cm at baseline
to three cm after four months of receiving 200 mg testosterone
cypionate every other week (226). Related outcomes had been observed in a research administering 1.000 mg testosterone undecanoate every
three months (227). Clitoral size was unaffected by a lower dosage of 25 mg
testosterone enanthate weekly for 24 weeks
in hysterectomized ladies (224). Thus, in distinction with dysphonia and hirsutism, there appears to be a higher threshold of androgenic action required for this side
impact to occur.
This is only really helpful for long-time, extremely skilled, or older
customers who haven’t any concerns about natural testosterone levels.
Some imagine very long cycles starting from three to 9 months can deliver permanent positive aspects.
Testosterone Enanthate (Cypionate) is the compound mostly
utilized in an extended cycle. As anticipated, the heightened risk of significant side
effects of those extra-long steroid cycles makes it a method that shouldn’t be
taken lightly. Anabolic steroids are orally-ingested, synthetic (man-made)
drugs that act like testosterone. They cause growth and improvement of male sexual organs, secondary intercourse
traits, and increases in muscle size and strength. But unlike males who will achieve little muscle with these “milder” steroids, ladies will find
that these are more than powerful sufficient to advertise nice muscle gains, together with fats loss and performance advantages.
Halotestin will improve power and power, and all this happens because it increases your pink
blood cell measurements. With such a excessive anabolic rating,
it’s simple to assume that you’ll get big anabolic results.
Nonetheless, the anabolic properties of Halotestin have little impact on people – most
of its results come from its androgenic properties. Mesterolone,
under the model name Proviron, is a helpful
slicing steroid for many who know the means to make the most of this
unique compound. While it can be used for mass features, this
steroid is especially utilized in cutting cycles.
Whichever method you go, you must ensure all the steroids are cleared out of your system earlier than beginning PCT.
This is the place understanding your steroid half-lives and clearance instances is crucial.
Studying about different people’s experiences with sure steroids on web forums and social media doesn’t put together you for what YOU will experience with the identical
steroid.
Bodybuilders use Sustanon 250 to realize bulk and muscle
mass, improve recovery, improve stamina and vitality, and retain a heightened anabolic
state. Deca-Durabolin has extra distinctive benefits like
boosting immunity, bone density, and joint health, which can be a few of the primary causes folks use
it. Deca will aid in power and mass gains with out worrying about estrogenic unwanted effects.
It can cause some androgenic results like hair loss and is taken into account delicate in comparability with
other compounds. Nandrolone Decanoate (Deca) is among the most generally used androgenic-anabolic steroids.
It’s important to get their suppressed testosterone again in normal working
order. This is amongst the important advantages girls have over males when using these substances.
As we can see, female steroid cycles are simple and fairly simple compared with a few of the cycles that male customers
formulate, which often involve multiple compounds, pyramid-style dosing,
and for a lot longer lengths of the cycle.
Each girl will have a unique tolerance regarding how a lot adverse impact she is keen to cope with.
The most hardcore feminine bodybuilders may have a
high tolerance for extra severe unwanted effects and will
not even be overly bothered by this. Nevertheless, suppressing the event of male characteristics as a lot as possible for many different girls will be a excessive priority during the cycle.
Steroid abuse carries significant well being dangers similar to
cardiovascular disease, liver and mind damage and infertility.
They’re often used in mixture with other performance and image-enhancing medication (this known as “stacking”) as well
as medication to counter the unwanted effects of steroids.
This could be in a misguided attempt to treat sexual
dysfunction (that’s unrelated to legitimate androgen deficiency),
perceived “low T” or “male menopause”, or managing non-specific symptoms like
tiredness.
This article takes a deeper look into steroids and lays out every little thing you have to know on the subject.
Using steroids can have an result on your capability to sleep, especially when taken before going to mattress in the night.
This is why many physicians suggest taking the entire daily dose in the morning.
Many younger boys and adults become too involved
with their physical appearance, which may result in a disordered body image,
also called muscle dysmorphia. This is a psychological well being situation where people are continually worrying about the flaws in their physical look.
If you’ve ever puzzled how the cumbersome weight lifters down at
the fitness center get so big, sometimes it isn’t through a
strict routine of weight lifting and food regimen, but through the illegal use of steroids.
It’s best to concentrate on sustainable, wholesome methods to build muscle and stay
fit.
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12-Week Muscle Growth Cycleより:
2025年11月1日 12:44 PM
Unlike biking, where you might abruptly stop using steroids totally on the finish of a
cycle, pyramiding allows you to taper off slowly. So, one of the primary
reasons customers choose the pyramid technique is to help adjust
to higher doses while trying to avoid overloading the body’s natural hormone system and giving it time to readjust when the dosage is lowered in the second part of the pyramid.
As for outcomes, both oral and injectable steroids are more
than able to delivering powerful anabolic effects18.
Ultimately, your outcomes will come down to not the
administration kind of your steroids however
to how you utilize them, how you intend your cycles, and how optimal
your food regimen and coaching are!
There is drastically increased problem for physicians
when dealing with other anabolic steroids since practically all of
them are not sanctioned for medical functions or even human use.
Nonetheless, there is a large rising inhabitants who has used or continues to make use of these
agents. This creates the necessity for a higher understanding of these medication, particularly within the context of screening for adverse health results.
During the present time, there is no formal evidence-based steering on screening anabolic steroid
users for varied pathologies. Physicians are likely to rely on nationwide
screening guidelines because of the lack of proof on main prevention in this patient inhabitants.
Elevated recognition of AAS and improved knowledge of this patient population is
necessary, notably on circumstance that over 1 million Americans
have used anabolic steroids [4]. It outcomes from distortion of the androgen-estrogen stability during
or after administration of AAS.
Depending on the character and dose of these brokers, extra adverse health effects may be anticipated.
Similar to AAS, most of these products are illegally obtained and their high quality should be questioned.
It has also been observed that the androgen-AR complex upregulates AR-mediated transcription through c-SRC kinase interaction-driven phosphorylation (10).
Separate from the AR, androgens could bind to steroid-hormone binding globulin (SHBG), activating the
SHBG receptor and rising protein kinase A (PKA) exercise (10).
This elevated PKA activity influences subsequent AR-mediated transcription via an alteration of both androgen membrane binding websites or by membrane Ars
(mARs) in SM cells (10). The mARs are functionally
separate from the intracellular Ars, while still presenting the necessary characteristics of being saturable and androgen-selective of a binding web site (10).
Methyltestosterone is a very basic anabolic-androgenic steroid (AAS),
with the only addition being a methyl group at C-17.
This eliminates first-pass degradation in the liver, making oral dosing possible.
AASs are medicine derived from the modification of the testosterone molecule to find
a way to augment or restrict certain traits of testosterone.
You must learn the pros and cons of each kind of anabolic steroid, who’s greatest suited to particular cycles, and
what steroid compounds are best used for bulking,
cutting, or power cycles. There’s no one-size-fits-all approach,
so what works for the next guy might not be best for you
at all.
Ingestion of DHEA can result in a rise in circulating DHEA
and androstenedione, however it’s not resolved as as to whether
there is an increase in plasma testosterone, see
for example Brown et al. (1999). This isn’t a surprise because in the grownup males the
general peripheral contribution of these precursor steroids to circulating testosterone is small.
Any contribution from exogenous DHEA or androstenedione will be largely moderated by the large quantity of testosterone contributed by the testis.
In girls, a rise in efficiency could also be potential following ingestion of
those supplements, as circulating testosterone would
be anticipated to increase. The plasma focus of endogenous testosterone is
roughly 1/10th that present in males and the relative proportion arising from peripheral conversion of
weaker androgens is far larger. Even though only 12–14% of
androstenedione is transformed peripherally to testosterone (Horton and Tait, 1966;
Bardin and Lipsett, 1967), this amount accounts for about half the circulating testosterone
within the women. As the peripheral contribution to blood testosterone is way higher within the young adult ladies than the boys, ingestion of modest amounts of androstenedione,
DHEA or androstenediol (the pure steroid or the Δ4 analogue) is more probably to considerably increase circulating testosterone.
The HAARLEM research, nevertheless, discovered no interaction between blood pressure and echocardiographic parameters – most likely because the increase was mild and of comparatively
quick period (97). Future research is critical to explore
the efficacy of blood pressure-lowering medication in this group of sufferers as
no trial thus far has evaluated this. When contemplating pharmacological treatment, angiotensin-converting
enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) may be preferrable over different blood
pressure-lowering medication as they do not affect train capacity (98).
Moreover, they don’t appear to be on the present record of prohibited
substances and methods of the World Anti-Doping
Association, which might – paradoxically – be related for some
AAS users. Alternatively, or additionally, calcium channel
blockers are a preferred choice in athletes (98).
Anabolic steroids are managed substances in several international locations, including Australia, Argentina,
Brazil, Canada, the United Kingdom and the United States.
Even so, there’s a readily available supply of steroids worldwide for non-medicinal
functions, because, in most international locations, anabolic steroids could be sold legally without a prescription (Hermansson,
2002; Cramer, 2005). Thus, many international distributors don’t violate the legal guidelines of their very own nation when they promote these substances
to clients abroad through the Web and by e-mail orders.
The majority of the hormone products in the European market come from countries
throughout the European Union and Russia, but also generally from Thailand, Turkey, Egypt, India and Pakistan (Hermansson, 2002).
In the United States, important portions of anabolic steroids come
from Mexico, as properly as different international locations corresponding to Russia, Romania
and Greece (Cramer, 2005). These drugs might lower the harm that happens to muscles throughout a hard workout.
Solely about one half of analyzed AAS samples contained the AAS kind as
indicated on the label and more typically than not the samples contained AAS
varieties not indicated on the label. We suspected that roughly 40% originated from
Jap Europe and Asia, whereas 60% appeared to be produced domestically in unlawful,
so called underground laboratories. Underground labs
are improvised labs hidden in cellars or warehouses the place raw materials, principally originating from Asia, are processed into tablets and injectable depots.
If the sperm rely is severely compromised 6 months after the final injection and the
affected person denies AAS use in the last months, blood needs to be examined to verify gonadotrophin and testosterone ranges.
As stated beforehand, the recovery part after current AAS use is characterised by low gonadotrophins,
low testosterone and low SHBG ranges. If gonadotrophin ranges are elevated, especially
if FSH is disproportionally elevated compared to LH,
major gonadal dysfunction, unrelated to steroid abuse, should be suspected.
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