一瞬、千原ジュニアに見えて疲れてるかも

2024年5月9日

RT @Uranium_chann: 一瞬、千原ジュニアに見えて疲れてるかも

— 銃とバッジを置いていけ＆ニチカン　共同運営アカウントをスタート (@kokosatoh)
May 5, 2024

[INOUE1]

これだけ拡散されると、どうしても一定数ホンモノの写真だと勘違いしてしまう勢が現れるので、念のためマジレスしておくと……これは下の画像↓をもとに作られたフェイク画像です。 pic.twitter.com/WDaQl65mns

— かみゅ (@kamyu_25) May 5, 2024

本当に僅か一瞬だけ戸田恵梨香に見えた俺はGW終了の終わりのショックで精神が疲弊してるんだと思う

— ジャンプ坊主@YouTubeと漫画とラーメン大好き！地震速報警戒中！ (@kaede331a) May 5, 2024

千原ジュニアじゃないの❓

— イキテレラ (@mtfkg5) May 5, 2024

一般ニュース解説

北朝鮮ミュージックビデオが秀悦すぎて、欧米で大ヒットの予想 15秒後流れます

客「Amazonに冷蔵庫を設置させたら、床を傷つけられた…」

コメント一覧

PedsEliteより:
2025年11月1日 5:17 PM
Interpretation of the neurotransmitter results is difficult by the
reality that different studies examined completely different brain areas, employed completely different methods,
and AAS exposure times. When abused like this, testosterone and other androgens can have damaging effects on the physique.
Other observed side effects embody zits vulgaris, breast growth, mental well being disorders, lowered sperm count, cardiovascular disease, and liver most cancers.
Nevertheless, when testosterone is used inside the context
of an approved therapeutic dose, as in testosterone substitute remedy, it carries a a
lot decrease danger of unwanted side effects. It has additionally been noticed
that the androgen-AR advanced upregulates AR-mediated transcription via c-SRC
kinase interaction-driven phosphorylation (10).
Separate from the AR, androgens might bind to steroid-hormone binding globulin (SHBG),
activating the SHBG receptor and increasing protein kinase A (PKA) exercise (10).
When this steroid is used, it undergoes a process called aromatization,
changing into estradiol, which is a form of estrogen. Some people are extra susceptible to experiencing estrogenic side effects due to this conversion. First,
the use of the AAS amongst bodily education students is in all probability going underestimated
as a result of self-reported health practices are weak to social desirability bias.
Second, through the ongoing COVID-19 epidemic, social distancing laws prevented more correct actual practices.
Roughly 3% of our examine participants currently use AASs—all men—which
is low compared to the findings of other research the place the prevalence was
18%, 23%, and 9% in Eastern SA, Kuwait, and Sweden, respectively23.
Moreover, the Riyadh research carried out by Al Jabri et al.
and Al Harbi et al. had high prevalence rates of 30.5% and 29.3%, respectively24,25.
This could be attributed to the fact that the population in these research was composed of male
gymnasts who have been older than our research individuals.
In our expertise, most customers of AAS use the internet as a source of knowledge, but retrieve merchandise via native dealers.
With some expertise, abusers of anabolic steroids are simply
spotted based on physical look. A short dialog
with such a person within the gym usually suffices to retrieve information about the local supplier.
Although promoting and shopping for of AAS is prohibited in most countries,
the possibilities of being caught are negligible.
The reliance of a feminine participant of this research on a couple of ‘women-only’ platforms exemplified the shortage of
tailor-made resources for that sub-population [66, 67] [63,64,65].
The action of anabolic steroid in increasing skeletal muscle mass and energy in women just
isn’t questioned. Male and feminine athletes from the German Democratic Republic (GDR), from about
1972 onwards did exceptionally well in international events, being consistently within the high rating of medal winners.
Sporting performance amongst their female athletes, particularly
in strength-dependent occasions, was spectacular.
Following the reunification of Germany in 1990, ground-breaking documental research was
made by the previous athlete, Mrs Brigitte Berendonk, and her husband Professor Werner Franke,
who had succeeded in buying a selection of highly classified scientific
stories that had not been destroyed.
Any DHT-lowering impact might be simply compensated for by the elevated
androgenic action of supraphysiological circulating testosterone levels.
Furthermore, different commonly used AAS are both already 5α-reduced, similar to methenolone,
drostanolone, stanozolol, oxandrolone and oxymetholone, or do not undergo important 5α-reduction within the human body, similar
to boldenone, trenbolone, methandienone, turinabol and
fluoxymesterone (24, 76). One notable exception is nandrolone, which is converted into dihydronandrolone (DHN) by 5α-reductase.
Nonetheless, whereas testosterone is converted into the stronger androgen DHT by 5α-reductase (21), the conversion of nandrolone into DHN yields an androgen with significantly lower binding affinity for the AR (77, 78).
Thus, whereas testosterone’s actions might be
amplified in tissues expressing 5α-reductase, nandrolone’s actions may be diminished (21).
On the basis of this metabolism, the combination of a 5α-reductase inhibitor with nandrolone seems significantly misguided.
Anabolic-androgenic steroids (AAS) are synthetic
hormones that enhance human performance.
Testosterone was first discovered in 1935, and in 1937 it was first used clinically3.
The discovery of the anabolic properties of AAS resulted in AAS use propagating into elite sports within the
1950s4. It was not until the late 1980s that
use gained floor among gym members within the common inhabitants and is today primarily used to enhance physique image and
construct muscular tissues extra easily5,6,7.
Recent estimates counsel that about 2–3% of the population have used AAS at
some point5,6, however greater prevalence is seen among men6 and subpopulations similar to leisure weightlifters, bodybuilders, inmates8 and substance
use patients9. Anabolic androgenic steroids (AAS) comprise testosterone and its artificial derivatives.
The different websites only accepted third-party
methods of fee corresponding to money orders or Bitcoin. All of the
websites, besides anabolics.com, utilized worldwide pharmacies as suppliers (Table 2), with
every displaying legal disclaimers relinquishing
duty for compliance with local laws regulating drug
use to the patron. Many of the worldwide pharmacies possessed individual websites with general information, however some
did not, corresponding to Scrioxx. Anabolic steroids promote muscle constructing
and the development of male sexual traits, which is why they could be medically prescribed to deal with delayed puberty, hormonal issues, or muscle loss from sure illnesses.
While they are beneficial in these controlled medical
treatments, their misuse can lead to extreme health issues.
Users usually take doses a lot larger than medically recommended, leading to various side effects.
These plants produce tubers, which accumulate massive amounts of bitter
spirostane saponins, principally diosgenin, with smaller amounts of its 25β-epimer yamogenin (53, Figure 10).
Although pharmaceutical T and other steroidal hormones are
obtained via the chemical conversion of diosgenin (as indicated
in Determine 2), there is not any evidence that common consumption of diosgenin will increase T levels in the human body.
Dietary Supplements containing Dioscorea extracts are also taken to treat symptoms of menopause in ladies, as a substitute for
hormone substitute remedy, however once more, there is not a definitive proof
that these saponins are metabolized to progesterone.
As A Substitute, the evidence signifies that the impression of AAS throughout puberty is modulated partly
by the environmental context by which the social interplay occurs.
The hormonal status of the conspecific rat performs a
vital function in determining whether aggression might be exhibited.
It has been demonstrated that adolescent AAS-treated
males can discriminate the hormonal states of their opponents, as
evidenced by elevated aggression in course of gonadally intact males, however not castrated
male rats (Farrell and McGinnis, 2003). A Quantity Of studies have been designed to research quite lots
of variables which may influence aggressive responses in adolescent males uncovered to AAS.
The information derived from these studies have been instrumental
in demonstrating that a number of experiential elements affect the display of aggression in AAS-treated males.
Factors which were recognized are the hormonal status,
the environmental context, physical provocation and the perceived risk through the
social encounter. The results of the research confirmed that there is a low degree of information about unwanted effects.
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