小池＆乙武　嘘つきカップル〈カイロ大卒業詐称疑惑再び〉「れいこさんと話すとイジメられる」「みんな“おかしい”と思っても言えない」小池都知事を4年間追求した上田令子都議が感じていた“ファシズム”のような空気これ以上独裁者をのさばらせてはいけない#小池百合子…

2024年4月18日

RT @uedareiko: 拡散希望‼️〈カイロ大卒業詐称疑惑再び〉「れいこさんと話すとイジメられる」「みんな“おかしい”と思っても言えない」小池都知事を4年間追求した上田令子都議が感じていた“ファシズム”のような空気

これ以上独裁者をのさばらせてはいけない
#小池百合子…

— 銃とバッジを置いていけ＆ニチカン　共同運営アカウントをスタート (@kokosatoh)
Apr 17, 2024

快適に読書ができる電子書籍のダウンロード販売サイトです。 国内最大のマンガ（電子書籍）販売サイト！

元ジャーナリストのAさんが声明文の原案を作成した翌日に、カイロ大学の学長のサインが入った声明文が送られて来た。
日本の都道府県から都道府県へ速達で翌日到着するが、
エジプトからは物理的に不可能。
早くて１週間は要する。 pic.twitter.com/JIG264xcRd

— 🇯🇵ケンサク (@kensaku0617) April 17, 2024

一般ニュース解説

これも非常に興味深いデータ。アメリカにおける海外からの留学生数国別ランキング。1992年から2022年はまさに失われた30年。はい、別にアメリカに留学生を大量に送ったからと言って偉いわけではないです。しかし日本はランキングを落とすだけではなくて…

韓国人「日本の学校に生理休暇が導入される」→こういうのって韓国の10年後を追ってるね | ニチカン！ https://t.co/4NfiwU8uN2

コメント一覧

Brandiより:
2025年3月21日 4:15 AM
This kind binds creatine to magnesium, claiming to enhance absorption and
provide extra advantages like improved muscle relaxation. Creatine Monohydrate + HCl is
another in style type, created by binding creatine to hydrochloric acid.
Although some types of creatine could also be more soluble when mixed in fluid, the evidence thus far reveals that creatine monohydrate could
additionally be the only option… It’s backed by the strongest
analysis, with research demonstrating its effectiveness at rising your
body’s shops and enhancing train performance. There’s strong proof that these supplements can improve
exercise efficiency (8, 15, 16). Creatine monohydrate has been out there for
a long time, making it essentially the most inexpensive type of creatine complement.
Creatine monohydrate is secure to consume for both short-term and long-term use.
As mentioned above creatine HCL has shown better solubility than monohydrates.
It is believed that due to better solubility creatine HCL gets absorbed higher.
Creatine supplementation could additionally be more practical when mixed with carbohydrates during
the first few days of supplementation. Creatine is an amino acid derivative
constructed from arginine, glycine and methionine.
It is produced naturally by the physique within the kidneys, liver,
and pancreas at a price of about 1-2 grams/day.
Creatine can be obtained from food (particularly red meat) and supplementation. Although creatine powder is likely one of the most
studied dietary dietary supplements, examine along
with your healthcare supplier in case you are also taking different drugs whereas consuming creatine powder.
Your healthcare supplier can use urine samples to test creatinine ranges and learn more about your
kidney well being. If creatinine levels remain high for an prolonged
time frame, you may be more at risk for persistent kidney illness
and kidney stones from the build-up of waste in your physique.
A total of 1322 articles had been reviewed with related research highlighted in this systematic review.
Creatine is most commonly current in dietary supplements in the form of creatine monohydrate, as a end result of
it will increase its bioavailability. Most producers supply creatine powders, which can be diluted in water or any other
fluid. Anabolic steroids may be taken orally, however can be injected subcutaneously (right beneath the skin).
Hope the detailed analysis has given you a clear overview of what’s
creatine nitrate vs monohydrate and which one you like.
On days 7 and 28, efficiency evaluations such as a bench press test, a Wingate take a look at, and a sprint on a bicycle
ergometer were carried out. Here we’ve gone by way
of the distinction between creatine monohydrate and creatine nitrate which comparatively
makes your analysis easier. Some of the side effects of creatine
monohydrate consumption include Gastrointestinal Misery, weight achieve, Muscle cramps, Abdomen upset, Diarrhea, and Dizziness.
Employing the really helpful dosage might be
better to eliminate these unwanted effects.
With a handy unflavored type, it can easily be combined with
any drink of your alternative. Creatine has also been proven to accelerate restoration by lowering muscle injury and irritation after intense exercise.
Rising research even suggests potential benefits for brain well being, indicating
that creatine may provide neuroprotective effects and enhance cognitive perform,
especially beneath circumstances requiring quick considering
and problem-solving. Di-Creatine and Tri-Creatine Malate These forms of creatine are creatine bonded with malic acid.
Di-creatine malate is made up of two creatine molecules
and tri-creatine malate is manufactured from up three. Neither
kind appears to supply any advantages over common creatine monohydrate.
The solely draw back to creatine monohydrate is that it does trigger some bloating and water retention in some users.
Unfortunately, a lot of the restricted creatine
supplementation research performed investigating the expression of CreaT has been via animal
fashions, as beforehand famous. However, independent of which
dosing technique is adopted, some researchers have observed no enchancment
in either rising intramuscular creatine or
efficiency measures via creatine supplementation. Creatine is a nonessential dietary compound
that is both endogenously synthesized, primarily in the liver, and naturally
ingested through omnivorous diets, with the greatest natural amount of creatine current in pink meats.
Creatine synthesized from the liver is launched
into the bloodstream and then taken up by muscle fibers predominately by the use of a
sodium-chloride dependent creatine transporter, CreaT1 [5].
There are actually two isoforms of creatine transporters, CreaT1 and CreaT2, of
which the latter is primarily active and present throughout the testes [6].
Creatine ingested through supplementation has been observed to be absorbed into the muscle solely
by means of CreaT1.
Product prices vary relying on a few elements,
similar to the sort of testing and processing a method undergoes,
in addition to any certifications it garners.
Typically speaking, micronized creatine might value more since it undergoes further
steps to realize its smaller particle size. Creatine monohydrate is
mostly more inexpensive since it’s bought in its purest form.
As the most versatile of the creatine sorts, creatine monohydrate is available in a
number of types, together with as a capsule, powder, or capsule.
In this explainer, we take a extra in-depth take a look at
these two forms of creatine, including their similarities
and variations, and if one is actually extra beneficial than the other.
However there’s a lot more to learn about these two forms of creatine, which is extremely in style within the complement area.
Creatine monohydrate doesn’t dissolve properly in water,
which causes abdomen discomfort when taken in high doses.
Kre-Alkalyn dissolves completely in the water, making it superior to creatine monohydrate supplements.
Creatine Monohydrate (CrM) is the preferred and broadly researched supplement ever produced.
Since its introduction in 1993, hundreds of people have turned
to creatine as a supplement for enhancing muscle mass, strength, and endurance.
Creatine works by converting into creatine phosphate, which aids in replenishing ATP (adenosine
triphosphate) molecules, that are thought of the first
energy supply in cells.
With Out this section, the muscular tissues and your workouts won’t
reap all of the benefits. You need to look carefully
to see the distinction between these sorts of creatine dietary supplements as a end result of the differences exist at a
molecular stage. As you can see, there are no other
types of creatine available on the market at this time which may be scientifically proven to be superior to creatine monohydrate.
It is the superior choice as a outcome of amount of
research and studies carried out on the supplement.
If you’re new to creatine supplementation, you in all probability marvel
which sort is best for you. In this double-blind study, subjects had been divided into 4 groups to match the effects of creatine
hcl vs monohydrate on athletic performance, plasma testosterone,
and plasma cortisol. In this text, we’ll deep dive into the differences
between these forms of creatine dietary supplements. We’ll
talk about every little thing from their safety, effectiveness, and the easiest way
to make use of them. The drawback is that creatine HCL is new,
so little or no research is available.
Many supplements are created to be extremely safe
and efficient, however understanding what to search for is past necessary for lots of firms could put components of their formulas that simply don’t need to
be there. When it involves creatine, the formula is pretty
easy and couple that with an efficient muscle-building complement and it’s no marvel why this has grown with such reputation for efficiency objectives.
The acute protective results of creatine on the central nervous system (CNS) have long been known. Similar to the effect within the myocardium, power buffering for short-term hypoxic conditions
could be achieved by saturating intracellular PCr. This might lead to protection in opposition to ischemia
and cell death, as nicely as calcium gradients created
by mechanical stimuli [204,205,206]. In animal experiments,
researchers have been in a place to show that idiopathically brought on brain damage and spinal cord injuries developed
to a lesser extent after creatine oral administration [207,208].
Creatine’s primary function is to rapidly produce vitality as a part of the
phosphocreatine system. Vitality for human exercise is derived from the breakdown of adenosine triphosphate (ATP) into adenosine diphosphate (ADP) and inorganic
phosphate (Pi). In the phosphocreatine system, phosphocreatine breaks down into
inorganic phosphate and creatine using the enzyme creatine kinase.
The inorganic phosphate can then help create power, e.g.
adenosine triphosphate (ATP), when added to adenosine diphosphate (ADP).
This ultimately makes a number of brands supply the supplement,
which raises competitors. Due to excessive demand out there, creatine monohydrate
is commonly more affordable. Since creatine monohydrate has been broadly used for decades and is mass-produced, making it accessible to a broad vary of customers.
When selecting between Creatine Nitrate and Creatine Monohydrate based mostly on their formulations, it’s essential to consider components corresponding to purity,
solubility, and potential components. Furthermore, the responses to
the supplementation of both in the body may be different for people.
Your body naturally produces this molecule, which serves quite
lots of essential features, together with energy production (1).
From the best creatine pills and powder to kre-alkalyn, creatine
HCL or the most effective vegan creatine, listed here
are the best creatine supplements available in the market.
Most research has been performed on the creatine monohydrate than any other form of creatine.
According to research studies, 5 g of creatine HCL helped
to construct a strong relationship between power and physique composition. A well-researched complement, creatine is
confirmed to be effective in building muscular tissues and enhancing strength.
Leonard’s articles have been printed in plenty of prime publications around the
internet.
It plays an important function within the fast manufacturing of adenosine triphosphate (ATP), the primary power currency of the cell.
When our muscles contract vigorously throughout activities like sprinting or weightlifting, ATP
is rapidly consumed, and creatine phosphate acts as
a direct reserve to replenish ATP, thus sustaining high-intensity
muscle activity. Have you ever puzzled what fuels your muscles throughout
an intense workout or a sprint? This compound plays
an important function in the fast vitality production needed for high-intensity bodily activities.
Understanding creatine phosphate is not just for
athletes or health enthusiasts; it’s valuable knowledge for anybody excited about how our bodies perform at their peak.
Consuming creatinine helps enhance muscle mass by rising the amount of time it takes for your
muscle tissue to interrupt down over time as you age. A healthcare supplier may suggest
them for aged or immunocompromised people to build muscle energy.
Nevertheless, it can be used for people who experience stomach upset with
creatine monohydrate. With better absorption and solubility, there are fewer side effects for
creatine HCL. Creatine combines with phosphate to kind creatine phosphate, which performs
a major position in mobile vitality production (5).
It helps within the formation of adenosine triphosphate (ATP), which is a major supply of mobile energy.
If you’re on the lookout for a great sports activities complement to improve
your athletic performance, then creatine supplements could be a nice choice.
According to the Nationwide Collegiate Athletic Affiliation Nationwide Study
of Substance Use Habits of Faculty Student-Athletes, about 14% of athletes reported
utilizing creatine supplements. A registered dietitian explains
what creatine does and assesses the benefits and risks.
But first, it is a compound that mixes creatine with one molecule of water, hence the name “monohydrate.” Creatine itself is a naturally occurring substance present in muscle cells, which helps produce power during high-intensity exercise
or heavy lifting. At its core, creatine increases
the provision of creatine phosphate in your muscle
cells. This molecule is a key player within the synthesis
of adenosine triphosphate (ATP), which is also known as the “vitality forex” of the cell (Wu, S et al., 2022).
Creatine phosphate donates a phosphate group
to the depleted ADP (adenosine diphosphate), regenerating it back into ATP.
This process boosts your capability to perform at most
depth for an extended period of time. Creatine phosphate, also known as phosphocreatine, is a naturally occurring substance within our
muscle cells.
Nonetheless, many customers report experiencing noticeable enhancements in efficiency and muscle improvement within two to four weeks of consistent use.
For optimum absorption, it is strongly recommended to supplement with 3-5g of creatine per day, in accordance with this study.
It is hypothesized that this dosage could
have a bigger bioavailability than dosages above 10g per serving.
Creatinol-O-phosphate, on the opposite hand, is a synthetically created compound analogous
to creatine and provides some comparable benefits. However,
unlike creatine, creatinol-O-phosphate is proof against a course
of referred to as cyclization — a chemical process where chemical molecules form a ring with different molecules.
When cyclization takes place in creatine, it produces a by-product often identified as creatinine.
In distinction, creatinol-O-phosphate maintains its structural integrity, allowing the body to achieve the complete good factor about its presence (x, x).
However, numerous totally different types of creatine have been purported to be more efficacious than CrM.
Neurodegenerative diseases are normally characterised by the destruction or dysfunction of neurons
in a specific mind space. Depending on the affected brain area,
course, and severity, the forms of the illness differ.
These embody Alzheimer’s illness (MA), amyotrophic lateral sclerosis
(ALS), a quantity of sclerosis (MS), Huntington’s disease (MH), and Parkinson’s disease (MP).
Impaired vitality balance with mitochondrial dysfunction and oxidative stress are
frequent to all ailments [238].
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